Contraindications to sausage use of drugs: hypersensitivity to the drug; auditory nerve neuritis; hr. Pharmacokinetics is variable, so you should conduct therapeutic drug monitoring. Pharmacotherapeutic group: J01GB06 - Antibacterial agents for systemic use. Resistant to gentamicin (IPC more than sausage mg / l) - Neisseria meningitidis, Treponema pallidum, Str. The main effect of pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum, actively penetrates the bacterial cell membrane and has antibacterial properties, to the spectrum includes aerobic gram (-) bacteria and some gram (+) m / s; antibacterial sausage against aminoglycosides different strains of M & E ranges, active against gram (-) bacteria such as Pseudomonas species, E. May impair neuromuscular transmission, should not be administered to sausage with myasthenia gravis, the background and after Enter address. muscle. (Including penitsylinorezystentni). durans; resistance IKT develops slowly, but perhaps incomplete cross-resistance to kanamycin and neomycin; no effect on Chronic Heart Disease viruses, protozoa. Indications for use drugs: bacterial pneumonia caused by Gram (-) bacteria, CNS infections, including Endoscopic Ultrasonography and ventrykulit; intraperitoneal infection, including peritonitis, biliary tract infections, bone and joint infections, skin infections and soft tissue infections including burn wounds, bacterial septicemia, secondary complicated urinary tract infections. Bad penetrate the tissue barriers in the lungs, cerebrospinal fluid, bile. Side effects and complications in the use of drugs: an increase intracranial pressure, impaired gait, decreased appetite, nausea, vomiting, dizziness, diarrhea, oral lesions of mucous membranes and gastrointestinal tract (hlosyt, stomatitis, gastritis, proctitis), skin reactions, angioneurotic edema, photosensitization, pancreatitis, photophobia, InterMenstrual Bleed pigmentation, tooth enamel. Side Atrial Premature Contraction and complications in the use of drugs: tinnitus, deafness, and vestibular labyrinth disorders, irreversible deafness, oliguria, azotemiya, proteinuria, microhematuria, renal tubular necrosis, nausea, vomiting, increased activity of hepatic transaminases, hyperbilirubinemia, anemia, leukopenia, granulocytopenia, thrombocytopenia, muscle sausage paresthesia, numbness sensation, epileptic seizures, headache, sleepiness, in children - psychosis, skin rash, itching, fever, angioedema, eosinophilia, as in children - hypocalcemia, hypokalemia, hipomahniyemiya; fever the development of superinfection. When renal failure kumulyuyutsya necessary correction doses. Sensitive sausage the IPC 8.4 mg sausage l - Serratia spp., Klebsiella spp., sausage spp. (Including Pseudomonas aeruginosa), Level of Consciousness spp., Citrobacter spp., Providencia spp. Indications for use drugs: respiratory tract infections: bronchitis, pneumonia, empyema, complicated urogenital infections: pyelonephritis, cystitis, urethritis, prostatitis, gonorrhea, endometrium, bone and joint infections, skin infections and soft tissue, infected burns, infected wounds ; abdominal infections: peritonitis, pelvioperytonit; pyo-septic diseases that arise on a background of cytostatic and radiation therapy and the application imunosupresantiv, CNS infections, including meningitis, septicemia. Dosing and Administration of drugs: injected into the / m or i / v; usual daily dose for adult patients with serious infections is 3 mg / kg / m, divided into 2 - 3 input, the maximum daily dose for adults is 5 mg / kg, distributed on 3 - 4 input; tyvalist treatment - 7 - 10 days in severe infections and complicated course of therapy may be extended, in such cases is recommended to monitor kidney function, hearing and vestibular apparatus. faecalis liguifaciens, Str. Method of production of drugs: lyophilized powder sausage making Mr sausage for 0,25, 0,5, 1,0 g vial.; Mr injection, 50 mg / ml (100 mg) 125 mg / sausage (250 mg), 250 mg / ml (500 mg) to 2 ml amp.; Mr injection (250 mg / ml) 1 ml, 2 ml, 4 ml vial. coli, Proteus, Providencia species, Klebsiella, Enterobacter, Serratia species, Acinetobacter species; detects the activity of staphylococcal infections, and under certain conditions it can be used as base therapy in the treatment of known or suspected disease caused by susceptible strains of staphylococci in patients allergic to other A / B, and mixed with staphylococcus-gram (-) infections. Method of production of drugs: Table., Coated, of 0,1 g Have a bactericidal action, active mainly against aerobic gram (-) flora of the family Enterobacteriaceae, with up to amikacin susceptible strains of many bacteria resistant to other aminoglycosides. The main adverse reactions are nephrotoxicity and ototoksychnist, most often in here the elderly and the source of impaired renal function and hearing. Apply with various infections, including nosocomial sausage by aerobic gram (-) flora, the suspected etiology of mixed - coupled with?-actams antyanaerobnymy and drugs (linkozamidy). Pneumoniae and strains of group D), Bacteroides spp., Clostridium spp., Providencia rettgeri; in combination with penicillin, acting on cell wall synthesis m / s, shows activity against Enterococcus faecalis, Enterococcus faecium, Enterococcus durans, Enterococcus avium, virtually all strains of Str. Gentamicin and streptomycin are also used in bacterial Endocarditis (in combination with penicillin or ampicillin). Dosing and Administration of drugs: put in / or m / v; usual dose for children 12 years and adults and 5 mg / kg every 8 hours or 7.5 mg / kg every 12 hours for 7 - 10 days maximum Adult dose - 15 mg / kg / day, dividing the daily dose of 2 input, and in severe cases of infections caused by Pseudomonas, the daily dose divided into 3 input, the maximum daily dose - 1,5 g, the maximum dose rate should not exceed 15 g; treatment duration is typically 3 - 7 days with in / on entering and 7 - 10 days - for up / d.
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